Multi-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution
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چکیده
منابع مشابه
Morphological changes in injured retinal pigment epithelium and photoreceptor cells after transplantation of stem cells into subretinal space
Introduction: Degenerative retinal diseases are main cause of irreversible blindness. Stem cells therapy is a promising way in these diseases. Therefore, mesenchymal stem cells because of its safety can produce degenerated cells and can play important role in treatment. The aim of this study was to examine morphological changes in injured retinal pigment epithelium (RPE) and photoreceptor cells...
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Antibody-mediated rejection is characterized by donor-specific antibody produced by B cells. However, to our knowledge, B cell invasion and antibody in the inflamed retina after transplantation of retinal pigment epithelial (RPE) cells has not been reported. To determine if RPE transplantation could be performed using allografts, we established in vivo immune rejection models with induced pluri...
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Adult human retinal pigment epithelium has been enzymatically isolated and established In tissue culture. Primary cultures survived three to six months. Occasionally, cell lines spontaneously evolved from primary cultures. Melanin granules decreased with the age of the culture, became less pigmented but retained some characterstics of melanin-producing cells. Lipofuscin granules are present, bu...
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Objective(s):The aim of this study was to evaluate distribution and changes of glycoconjugates of retinal photoreceptors during both pre- and postnatal development. Materials and Methods: Tissue sections from days 15 to 20 of Wistar rat embryos and 1 to 12 postnatal days of rat newborns including developing eye were prepared for lectinhistochemistry technique. Horseradish peroxidase (HRP)-label...
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Retinal pigment epithelial (RPE) stem cells offer a theoretical treatment strategy for a wide variety of retinal disorders including age-related macular degeneration (AMD) and retinal dystrophies. There are, however, a number of hurdles that will have to be overcome before a consistently reliable and successful therapy can be offered to patients. These include expansion of sufficient numbers of...
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ژورنال
عنوان ژورنال: Visual Neuroscience
سال: 2016
ISSN: 0952-5238,1469-8714
DOI: 10.1017/s0952523815000310